Inflammatory state of Type II diabetic patients with chronic ulcers in response to herbal treatment
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AbstractBackground: Type II diabetic patients easily develop ulcers over their feet which heal with great difficulties and not infrequently, end up in amputations. In the quest for innovative means to avoid amputation, herbal medicine has been used in China to heal ulcers. Method: A randomized placebo controlled clinical trial involving 80 patients was conducted to test whether a herbal formula taken orally could help to preserve the ulcerated leg. Other parameters measured included granulation maturation time, skin temperature and circulation, and tumor necrosis factor alpha (TNF-α). Results: showed a 85% limb rescue with the herbal treatment group showing superiority over placebo group. TNF-α decline was observed with gradual ulcer healing and the herbal supplement group showed a more impressive decline (p=0.037). © 2012 Elsevier Ltd.
All Author(s) ListLeung P.C., Pang S.Y., Wong E.L.Y., Cheng K.F.
Journal nameFoot
Volume Number22
Issue Number3
PublisherChurchill Livingstone
Place of PublicationUnited States
Pages181 - 185
LanguagesEnglish-United Kingdom
KeywordsChinese medicine, Diabetes, Wound healing

Last updated on 2020-07-07 at 00:41