A new density-ratio based approach for patient-specific biomedical monitoring
Refereed conference paper presented and published in conference proceedings


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AbstractIn order to denote the abnormalities of the patients, we propose a novel approach to detect anomaly in biomedical monitoring using density ratio values as the Patient Status Index (PSI). The key idea of the proposed method is to define the ratio of training and testing data densities, where training dataset only consist of normal data and testing dataset consist of both normal and abnormal data, and identify irregular samples for testing patients' dataset. Furthermore, we define four inequalities to denote the interval values of density ratio and give the corresponding status for patients. In addition, the applied Kullback-Leibler based algorithm for calculating density ratio values without involving density estimation is equipped with a cross validation (CV) model selection procedure, allowing us to objectively optimize values of tuning parameters. We select training and testing data from Physionet database to do our pilot experiment. The experimental results for 11901 beats show that the density-ratio based approach work very well in terms of specificity and sensitivity. © 2011 IEEE.
All Author(s) ListChen D., Meng M.Q.-H.
Name of Conference33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Start Date of Conference30/08/2011
End Date of Conference03/09/2011
Place of ConferenceBoston, MA
Country/Region of ConferenceUnited States of America
Detailed descriptionorganized by IEEE,
Year2011
Month12
Day26
Pages6943 - 6946
ISBN9781424441211
ISSN1557-170X
LanguagesEnglish-United Kingdom

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