Methy-Pipe: An integrated bioinformatics data analysis pipeline for whole genome methylome analysis
Refereed conference paper presented and published in conference proceedings


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AbstractBisulfite sequencing is used to detect the methylated status at single nucleotide resolution. Coupled with a recently developed next generation sequencing technology, it becomes a powerful tool for studying the epigenetic regulations in a variety of biological systems. However, due the large dataset generated from this kind of experiment, limited software packages are available for analyzing the resultant high-throughput bisulfite sequencing data with reasonable performance in terms of efficiency and accuracy. To solve this problem,, we developed an integrated data analysis pipeline Methy-Pipe for analyzing whole genome methylome data. The capability of it running in parallel on Linux cluster makes this pipeline superior to other exisetnent softwares. ©2010 IEEE.
All Author(s) ListJiang P., Sun X., Chen E.Z., Sun K., Chiu R.W.K., Lo Y.M.D., Sun H.
Name of Conference2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2010
Start Date of Conference18/12/2010
End Date of Conference21/12/2010
Place of ConferenceHongKong
Country/Region of ConferenceHong Kong
Detailed descriptionorganized by IEEE,
Year2010
Month12
Day1
Pages585 - 590
ISBN9781424483044
LanguagesEnglish-United Kingdom

Last updated on 2020-30-07 at 23:58