Sonodynamic action of chlorin e6 on Staphylococcus aureus and Escherichia coli
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AbstractBacteria remain a great threat to human health. In the present study, we examined whether sonodynamic action of chlorin e6 had antibacterial activity on gram-positive bacterial strain Staphylococcus aureus (S. aureus) and gram-negative bacterial strain Escherichia coil (E. coil). Colony forming unit (CFU) assay showed that sonodynamic treatment of chlorin e6 induced a 2-log reduction in CFU of E. coil cells, 7-log reduction in CFU of S. aureus. Fluorescent microscopy observed that dead cells remarkably increased whereas live cells decreased after sonodynamic treatment of chlorin e6 on S. aureus cells. We first demonstrated that sonodynamic action of chlorin e6 has antibacterial effect on both gram-positive and negative bacteria, more powerful on gram-positive bacteria. (C) 2015 Elsevier By. All rights reserved.
All Author(s) ListXu CS, Dong JH, Ip M, Wang XN, Leung AW
Journal nameUltrasonics
Year2016
Month1
Volume Number64
Pages54 - 57
ISSN0041-624X
eISSN1874-9968
LanguagesEnglish-United Kingdom
KeywordsSonodynamic action,Chlorin e6,Staphylococcus aureus,Escherichia coli
Web of Science Subject CategoriesAcoustics;Radiology, Nuclear Medicine & Medical Imaging;Acoustics;Radiology, Nuclear Medicine & Medical Imaging

Last updated on 2021-14-04 at 00:02