Imaging Plaque characteristics, burden and distribution assessment in an Asian population with high-resolution intracranial vessel wall imaging at 3 Tesla MRI
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AbstractPurpose: To qualitatively evaluate intracranial plaque characteristics (contrast enhancement, thickening and configuration (1), total plaque burden and distribution in patients with an middle cerebral artery (MCA) stenosis, using a 3D T1-weighted volumetric isotropic turbo spin-echo acquisition (VISTA) vessel wall sequence at 3T.

Methods: Nineteen Chinese ischemic stroke and TIA patients presenting with a symptomatic MCA stenosis underwent 3T MR imaging; the protocol included a Time-of-Flight Magnetic Resonance Angiography (TOF-MRA) and the T1w VISTA sequence before and after (83%) contrast administration. One observer reviewed the plaque characteristics.

Results: Vessel wall lesions were identified in 18 patients (95%), totaling 57 lesions in 494 segments (12% of segments). Most of the lesions were present in the anterior circulation. 75% of the lesions were eccentric (Fig. 1), 44% enhanced after contrast administration and 74% of the lesions were focal. Plaque burden and distribution are presented in Table 1.

Conclusion: Intracranial vessel wall imaging using a 3D T1w VISTA vessel wall sequence at 3T was able to identify basic intracranial plaque characteristics and assess total plaque burden and distribution. Most of the lesions were found in the anterior circulation, corresponding to similar distributions found for ischemic strokes (2).
All Author(s) ListNikki Dieleman, Wenjie Yang, Jill Abrigo, Ka Lok Lee, Chiu Wing Chu, Anja G. van der Kolk, Jeroen C.W. Siero, Ka Sing Wong, Jeroen Hendrikse, and Xiang Yan Chen
Name of ConferenceEuropean Stroke Organisation Conference 2015
Start Date of Conference17/04/2015
End Date of Conference19/04/2015
Place of ConferenceGlasgow
Country/Region of ConferenceGreat Britain
Journal nameInternational Journal of Stroke
Proceedings TitleInternational Journal of Stroke
Volume Number10
Issue NumberSupplement S2
PublisherSage Publications Ltd.
Pages310 - 311
LanguagesEnglish-United Kingdom

Last updated on 2018-22-01 at 21:26