Gelatin embedding: A novel way to preserve biological samples for terahertz imaging and spectroscopy
Publication in refereed journal

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摘要Sample dehydration has traditionally been a challenging problem in ex vivo terahertz biomedical experiments as water content changes significantly affect the terahertz properties and can diminish important contrast features. In this paper, we propose a novel method to prevent sample dehydration using gelatin embedding. By looking at terahertz image data and calculating the optical properties of the gelatin-embedded sample, we find that our method successfully preserves the sample for at least 35 h, both for imaging and spectroscopy. Our novel preservation method demonstrates for the first time the capability to simultaneously maintain sample structural integrity and prevent dehydration at room temperature. This is particularly relevant for terahertz studies of freshly excised tissues but could be beneficial for other imaging and spectroscopy techniques.
著者Fan S., Ung B., Parrott E.P.J., Pickwell-Macpherson E.
期刊名稱Physics in Medicine and Biology
出版年份2015
月份4
日期7
卷號60
期次7
出版社Institute of Physics Publishing
出版地United Kingdom
頁次2703 - 2713
國際標準期刊號0031-9155
電子國際標準期刊號1361-6560
語言英式英語
關鍵詞dehydration, gelatin, terahertz spectroscopy

上次更新時間 2021-13-01 於 01:16