Bone marrow perfusion of proximal femur varied with BMD - A longitudinal study by DCE-MRI
Refereed conference paper presented and published in conference proceedings


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AbstractThis study investigated bone marrow perfusion at proximal femur varying with bone mineral density (BMD) and aging over 4 years. Dynamic contrast enhanced MRI data was extracted pixel-by-pixel and classified into 3 patterns to indicate the perfusion function. Eighty-seven elderly females were involved. A notable reduced perfusion as a whole was observed in osteoporotic subjects. Moreover, perfusion distribution varies as BMD decreases, especially at the area crossing the femoral neck to the shaft. Consistent for all subjects, the perfusion decreases significantly from the lesser trochanter to the greater trochanter. Further, the subjects with good bone marrow perfusion would keep stable BMD after 4 years, while for those with bad perfusion, their BMD consistently decreased over 4 years. The results indicated that the bone marrow perfusion function interacts with bone modeling and could have a long term effect on BMD. A good perfusion function would help to keep the bone health. © 2013 IEEE.
All Author(s) ListMa H.T., Lv H., Griffith J.F., Yuan J., Leung P.-C.
Name of Conference2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Start Date of Conference03/07/2013
End Date of Conference07/07/2013
Place of ConferenceOsaka
Country/Region of ConferenceJapan
Detailed descriptionorganized by IEEE, EMB, JSMBE,
Year2013
Month10
Day31
Pages2607 - 2610
ISBN9781457702167
ISSN1557-170X
LanguagesEnglish-United Kingdom

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