Associations of uric acid and gamma-glutamyltransferase (GGT) with obesity and components of metabolic syndrome in children and adolescents
Publication in refereed journal


摘要Background: The combined effect of uric acid, gamma-glutamyltransferase (GGT) and cardiovascular risk factors clustering in the youth remains under-explored. Objective: The objective of this study was to examine the association between uric acid, GGT, obesity and the individual components of metabolic syndrome in children and adolescents. Methods: We performed a cross-sectional observational study of 2067 children and adolescents (875 boys and 1192 girls) aged 6-20 years who were healthy volunteers and were recruited from primary and secondary schools in Hong Kong between 2007 and 2008. Subjects were divided into two strata (75th percentile as cut-off) for comparison between odds of cardiovascular risk factors. Results: After adjustment by multivariable logistic regression, subjects in upper stratum, i.e. <75th percentile, of either serum uric acid or GGT levels were associated with obesity, low high-density lipoprotein cholesterol (HDL-C) level and high blood pressure (adjusted odds ratios [AOR] ranged from 1.63 to 5.82, all P
著者Kong A.P.S., Choi K.C., Ho C.S., Chan M.H.M., Ozaki R., Chan C.W.H., Chan J.C.N.
期刊名稱Pediatric Obesity
出版社Wiley-Blackwell for the International Association for the Study of Obesity
出版地United Kingdom
頁次351 - 357
關鍵詞Cardiovascular risk factors, Gamma-glutamyltransferase, Obesity, Uric acid

上次更新時間 2021-16-01 於 00:42