Associations of uric acid and gamma-glutamyltransferase (GGT) with obesity and components of metabolic syndrome in children and adolescents
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AbstractBackground: The combined effect of uric acid, gamma-glutamyltransferase (GGT) and cardiovascular risk factors clustering in the youth remains under-explored. Objective: The objective of this study was to examine the association between uric acid, GGT, obesity and the individual components of metabolic syndrome in children and adolescents. Methods: We performed a cross-sectional observational study of 2067 children and adolescents (875 boys and 1192 girls) aged 6-20 years who were healthy volunteers and were recruited from primary and secondary schools in Hong Kong between 2007 and 2008. Subjects were divided into two strata (75th percentile as cut-off) for comparison between odds of cardiovascular risk factors. Results: After adjustment by multivariable logistic regression, subjects in upper stratum, i.e. <75th percentile, of either serum uric acid or GGT levels were associated with obesity, low high-density lipoprotein cholesterol (HDL-C) level and high blood pressure (adjusted odds ratios [AOR] ranged from 1.63 to 5.82, all P
All Author(s) ListKong A.P.S., Choi K.C., Ho C.S., Chan M.H.M., Ozaki R., Chan C.W.H., Chan J.C.N.
Journal namePediatric Obesity
Volume Number8
Issue Number5
PublisherWiley-Blackwell for the International Association for the Study of Obesity
Place of PublicationUnited Kingdom
Pages351 - 357
LanguagesEnglish-United Kingdom
KeywordsCardiovascular risk factors, Gamma-glutamyltransferase, Obesity, Uric acid

Last updated on 2021-22-09 at 23:42