Prospective cohort study of compliance with faecal immunochemical tests for colorectal cancer screening in Hong Kong
Publication in refereed journal


摘要Objective: This study aims to examine the rate and determinants of faecal immunochemical test (FIT) compliance over a four-year period among asymptomatic participants in a colorectal cancer (CRC) screening programme in Hong Kong. Method: Self-referred screening participants aged between 50 and 70. years who chose FIT for annual screening were followed up for four years (2008-2012). All participants were reminded up to three times yearly for FIT retrieval within two months of the expected screening date. The proportions of screening participants who failed to adhere to annual FIT tests in 1, 2, 3 and 4-years, respectively, after the initial screening uptake were evaluated. The factors associated with non-compliance with FITs in any year were assessed by a binary logistic regression analysis. Results: From 5700 consecutive screening participants, the compliance rates to FIT were 95.1%, 79.9%, 66.2% and 68.4% at years one to four, respectively. The proportions of people missing one, two and three tests were 6.2%, 19.6% and 2.1%, respectively. From multivariate regression analysis, male subjects, younger participants, smokers and those with positive family history of CRC were more likely to be non-compliant. Conclusion: Participants identified as at higher risk for screening non-compliance should be especially considered for individual reminders to enhance screening effectiveness. © 2013 .
著者Wong M.C.S., Ching J.Y.L., Lam T.Y.T., Luk A.K.C., Hirai H.W., Griffiths S.M., Chan F.K.L., Sung J.J.Y.
期刊名稱Preventive Medicine
出版社Academic Press
出版地United States
頁次227 - 231
關鍵詞Colorectal cancer, Compliance, Determinants, Faecal occult blood, Screening

上次更新時間 2021-20-09 於 23:23