Cross Sectional Survey of Influenza Antibodies before and during the 2009 Pandemic in Shenzhen, China
Publication in refereed journal

替代計量分析
.

其它資訊
摘要Much information is available for the 2009 H1N1 influenza immunity response, but little is known about the antibody change in seasonal influenza before and during the novel influenza A pandemic. In this study, we conducted a cross-sectional serological survey of 4 types of major seasonal influenza in March and September 2009 on a full range of age groups, to investigate seasonal influenza immunity response before and during the outbreak of the sH1N1 influenza in Shenzhen - the largest migration city in China. We found that the 0-5 age group had an increased antibody level for all types of seasonal influenza during the pandemic compared to the pre-outbreak level, in contrast with almost all other age groups, in which the antibody level decreased. Also, distinct from the antibodies of A/H3N2, B/Yamagata and B/Victoria that decreased significantly during the 2009 H1N1 pandemic, the antibody of A/H1N1 showed no statistical difference from the pre-outbreak level. The results suggest that the antibodies against the 2009 sH1N1 cross-reacted with seasonal H1N1. Moreover, the 0-5 age group was under attack by both seasonal and 2009 H1N1 influenza during the pandemic, hence vaccination merely against a new strain of flu might not be enough to protect the youngest group. © 2013 Wu et al.
著者Wu C.-L., Lu J., Wang M.H., Lv X., Chen Y., Kung H.-F., Zee B., Cheng X.-W., He M.-L.
期刊名稱PLoS ONE
出版年份2013
月份1
日期29
卷號8
期次1
出版社Public Library of Science
出版地United States
國際標準期刊號1932-6203
語言英式英語

上次更新時間 2020-14-10 於 03:23