A randomized placebo controlled trial of an innovative herbal formula in the prevention of atherosclerosis in postmenopausal women with borderline hypercholesterolemia
Publication in refereed journal

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摘要Background: Danshen (Salvia miltiorrhiza) and Gegen (Radix puerariae) (D&G) are two herbs frequently used for the treatment of angina and other cardiac symptoms in Chinese materia medica. Recent studies have demonstrated their cardio-protective and anti-atherosclerosis effects. Earlier we have conducted two clinical trials in 2004 and 2007 which demonstrated such effects in extremely high risk patients. Study objective: The aim of the study was to demonstrate the safety and effectiveness of D&G in the prevention of atherosclerosis in postmenopausal women with early hypercholesterolemia. Design: The study was designed as a randomized, double-blinded, placebo-controlled trial with a 12-month treatment period. Subject: A population based sample of 165 postmenopausal women aged 47-65 were included in the trial. Only women who experienced menopause for more than 12 months were recruited. Interventions: The eligible subjects were randomized to take the D&G preparation (two capsules), or image-identical placebo capsules (two capsules) daily, in a double-blind and parallel fashion for 12 month. © 2014 Elsevier Ltd.
著者Kwok T., Leung P.C., Lam C., Ho S., Wong C.K., Cheng K.F., Chook P.
期刊名稱Complementary Therapies in Medicine
出版年份2014
月份1
日期1
卷號22
期次3
出版社Churchill Livingstone
出版地United States
頁次473 - 480
國際標準期刊號0965-2299
電子國際標準期刊號1873-6963
語言英式英語
關鍵詞Atherosclerosis, Herbal medicine, Hypercholesterolemia, Postmenopausal women, Prevention

上次更新時間 2020-27-09 於 00:42