Cumulative radiation dose from radiography in preterm infants during hospitalisation
Publication in refereed journal


摘要Objectives: Preterm infants with low gestational age (GA) and very low birth weight experience high morbidity
and mortality. Chest and abdominal radiographs are commonly performed in this group. The aim of this study
was to estimate the trend of radiation exposure from radiographs in preterm infants.

Methods: In this retrospective study, 210 surviving infants were systematically reviewed. The entrance skin air
kerma was measured followed by estimation of effective dose (ED) using the Monte Carlo simulation software
(PCXMC 2.0). We estimated the risk of radiation-induced cancers based on referenced risk factors from the
International Commission on Radiological Protection Publication 103.

Results: The median (interquartile range) GA, birth weight, and hospital stay of the infants was 29.2 (27.9-
31.1) weeks, 1.2 (1.0-1.5) kg, and 68.5 (47.0-100.0) days, respectively. The median ED per chest and abdomen
radiograph was 0.021 mSv and 0.026 mSv, respectively. Preterm infants with GA of <28 weeks received a median
cumulative ED (cED) of 1.47 mSv, those of 28 to <30 weeks received a median cED of 0.84 mSv, and those of 30
to <32 weeks received a median cED of 0.39 mSv. Preterm babies with lower GA and longer hospital stay were at
higher radiation risk from diagnostic radiography. Preterm infants with GA of <28 weeks and those who required
surgery due to necrotising enterocolitis had the highest dose of cED.

Conclusion: Preterm infants were not exposed to excessive radiation during hospitalisation; dose risk for
development of cancer was negligible. Nonetheless, the principle of ALARA (as low as reasonably achievable)
should be applied.
著者KYK Lau, SCN Hui, HM Cheung, PC Ng, WCW Chu
期刊名稱Hong Kong Journal of Radiology
出版社Hong Kong College of Radiologists
出版地Hong Kong
頁次183 - 191
關鍵詞Infant, newborn, Radiation dosage, Radiation protection, Risk assessment

上次更新時間 2020-15-10 於 02:20