Oral anti-diabetic pharmacological therapies for the treatment of women with gestational diabetes
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Gestational diabetesmellitus (GDM) is amajor public health issuewith rates increasing globally.Gestational diabetes, glucose intolerance first recognised during pregnancy, usually resolves after birth and is associated with short- and long-term complications for the mother and her infant. Treatment options can include oral anti-diabetic pharmacological therapies.

To evaluate the effects of oral anti-diabetic pharmacological therapies for treating women with GDM.
Search methods
We searched Cochrane Pregnancy and Childbirth’s Trials Register (14 May 2016), ClinicalTrials.gov, WHO ICTRP (14 May 2016) and reference lists of retrieved studies.

Selection criteria
We included published and unpublished randomised controlled trials assessing the effects of oral anti-diabetic pharmacological therapies for treating pregnant women with GDM.We included studies comparing oral anti-diabetic pharmacological therapies with 1) placebo/standard care, 2) another oral anti-diabetic pharmacological therapy, 3) combined oral anti-diabetic pharmacological therapies. Trials using insulin as the comparator were excluded as they are the subject of a separate Cochrane systematic review. Women with pre-existing type 1 or type 2 diabetes were excluded.

Data collection and analysis
Two review authors independently assessed trials for inclusion and trial quality. Two review authors independently extracted data and data were checked for accuracy.
All Author(s) ListJulie Brown, Ruch Martis, Brenda Hughes, Janet Rowan, Caroline A Crowther
Title of PublicationCochrane Database of Systematic Reviews
Volume NumberCD011967
PublisherJohnWiley & Sons, Ltd.
Place of PublicationUnited Kingdom
Pages1 - 110
LanguagesEnglish-United Kingdom

Last updated on 2021-24-09 at 23:53