Assessing the risk of dengue virus transmission in a non-endemic city surrounded by endemic and hyperendemic areas
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AbstractObjective: To assess the potential risk of dengue transmission in a non-endemic city using a spatial
epidemiological approach.
Methods: Past dengue exposure of the general population was examined by dengue virus (DENV) IgG
testing of archived samples from voluntary blood donors. Vector intensities were determined by local
ovitrap index (OI). Analyses were made in the context of population statistics at both the district and subdistrict
level.
Results: The overall prevalence of DENV IgG was low at 2.25%. Positive donors were more likely to be
older, non-Chinese, and female. Neither the OI nor the location of residence was associated with DENV
serology. The sub-district level OI was clustered, but no correlation could be confirmed with the location
of residence of positive blood donors.
Conclusions: The cumulative exposure of Hong Kong residents to dengue has so far been low. Coupled
with the lack of a spatial relationship between exposed cases and vector intensities, a high risk of local
transmission of DENV is not supported. The apparently higher exposure likelihood of females could be
explained by past infection in workers from dengue endemic countries, while frequent travel could have
exposed older adults to DENV. Continued surveillance, risk assessment, and intensive vector control
remain essential to prevent the transformation of a non-endemic to an endemic city.
Acceptance Date09/01/2017
All Author(s) ListKwan TH, Lee SS, Chan DPC, Cheung M, Kam KM
Journal nameInternational Journal of Infectious Diseases
Year2017
Month2
Volume Number55
Pages99 - 101
ISSN1201-9712
eISSN1878-3511
LanguagesEnglish-United Kingdom
KeywordsDengue, epidemiology, geographic information system

Last updated on 2020-24-09 at 02:14