Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine
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AbstractThe prevalence of cognitive impairment and dementia caused by cerebrovascular disease is likely to increase with the global aging population. Vascular contributions to cognitive impairment and dementia (VCID) is a wide spectrum term used to include a diverse heterogeneous group of cognitive syndromes with vascular factors regardless of the cause of pathogenesis. VCID ranges from mild cognitive impairment to full-blown dementia with vascular dementia (VaD) as the most severe stage. It is further complexed by the coexistence of other forms of dementia such as Alzheimer's disease (AD). Recent researches in the functions of the neurovascular unit (NVU) suggest that dysfunction of the NVU might be the cause of primary vascular events in the brain that leads to further neurodegeneration. In this review, we have briefly summarized various forms of VCID. There is currently no standard therapy for VCID or dementia. Given the fact that Traditional ChineseMedicine (TCM) has gained popularity worldwide, we also reviewed recent scientific and clinical findings on various antidementia TCM for the treatment of VCID, including Salvia miltiorrhiza, Huperzia serrata, Ligusticum chuanxiong, Ginkgo biloba, Panax ginseng, and also TCM formula Sailuotong capsule (SLT) and Fufangdanshen tablets (FFDS).
All Author(s) ListZhou XH, Cui GZ, Tseng HHL, Lee SMY, Leung GPH, Chan SW, Kwan YW, Hoi MPM
Journal nameEvidence-Based Complementary and Alternative Medicine
Detailed descriptionArticle ID: 9627258
Volume Number2016
Issue Number2016
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesIntegrative & Complementary Medicine;Integrative & Complementary Medicine

Last updated on 2020-23-11 at 01:18