Depression is common
following an acute stroke. Poststroke Depression (PSD) have notable impacts on
the function recovery and quality of life of stroke survivors. Incidence
decreased across time after stroke, but prevalence of PSD tend to be stable.
Vascular factors such as diabetes, hypertension and smoking have been related
to the development of PSD. Many studies have explored the association between
lesion location and the incidence of PSD. For example, lesions in frontal lobe,
basal ganglia and deep white matter have been related with PSD. Furthermore,
cerebral microbleeds and functional changes in brain networks have also been
implicated in the development of PSD. In this presentation, evidences of such
association between the above structural and functional brain changes and PSD
will be reviewed.