Functional magnetic resonance imaging techniques and their development for radiation therapy planning and monitoring in the head and neck cancers
Publication in policy or professional journal

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摘要

Radiation therapy (RT), in particular intensity-modulated radiation therapy (IMRT), is becoming a more important nonsurgical treatment strategy in head and neck cancer (HNC). The further development of IMRT imposes more critical requirements on clinical imaging, and these requirements cannot be fully fulfilled by the existing radiotherapeutic imaging workhorse of X-ray based imaging methods. Magnetic resonance imaging (MRI) has increasingly gained more interests from radiation oncology community and holds great potential for RT applications, mainly due to its non-ionizing radiation nature and superior soft tissue image contrast. Beyond anatomical imaging, MRI provides a variety of functional imaging techniques to investigate the functionality and metabolism of living tissue. The major purpose of this paper is to give a concise and timely review of some advanced functional MRI techniques that may potentially benefit conformal, tailored and adaptive RT in the HNC. The basic principle of each functional MRI technique is briefly introduced and their use in RT of HNC is described. Limitation and future development of these functional MRI techniques for HNC radiotherapeutic applications are discussed. More rigorous studies are warranted to translate the hypotheses into credible evidences in order to establish the role of functional MRI in the clinical practice of head and neck radiation oncology.

出版社接受日期27.05.2016
著者Yuan, Jing; Lo Gladys; King, Ann D
期刊名稱QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
出版年份2016
月份8
卷號6
期次4
出版社AME PUBL CO
頁次430 - 448
國際標準期刊號2223-4292
電子國際標準期刊號2223-4306
語言英式英語
關鍵詞Head and neck cancer (HNC); diffusion; hypoxia; magnetic resonance imaging (MRI); metabolism; perfusion; radiation therapy (RT)

上次更新時間 2021-19-01 於 02:00