A novel method for discovering local spatial clusters of genomic regions with functional relationships from DNA contact maps
Publication in refereed journal


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其它資訊
摘要Motivation: The three-dimensional structure of genomes makes it possible for genomic regions not adjacent in the primary sequence to be spatially proximal. These DNA contacts have been found to be related to various molecular activities. Previous methods for analyzing DNA contact maps obtained from Hi-C experiments have largely focused on studying individual interactions, forming spatial clusters composed of contiguous blocks of genomic locations, or classifying these clusters into general categories based on some global properties of the contact maps.
著者Hu XH, Shi CH, Yip KY
會議名稱24th Annual Conference on Intelligent Systems for Molecular Biology (ISMB)
會議開始日08.07.2016
會議完結日12.07.2016
會議地點Orlando
期刊名稱Bioinformatics
出版年份2016
月份6
日期15
卷號32
期次12
出版社OXFORD UNIV PRESS
頁次111 - 120
國際標準期刊號1367-4803
電子國際標準期刊號1460-2059
語言英式英語
Web of Science 學科類別Biochemical Research Methods; Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology; Computer Science; Computer Science, Interdisciplinary Applications; Mathematical & Computational Biology; Mathematics; Statistics & Probability

上次更新時間 2021-19-04 於 00:34