Plasma Osteopontin, Hypoxia, and Response to Radiotherapy in Nasopharyngeal Cancer
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AbstractPurpose: Recent studies have suggested that osteopontin is induced by hypoxia in head and neck cancer cell lines and its plasma level may serve as a surrogate marker for tumor hypoxia and treatment outcome in head and neck cancer. We investigated the response of osteopontin to in vitro hypoxia in nasopharyngeal carcinoma cell lines, and determined plasma osteopontin levels in nasopharyngeal carcinoma patients, nonnasopharyngeal carcinoma head and neck cancer patients, and healthy controls. We explored the relationship of plasma osteopontin and response to radiotherapy in nasopharyngeal carcinoma.
All Author(s) ListHui EP, Sung FL, Yu BKH, Wong CSC, Ma BBY, Lin XR, Chan A, Wong WL, Chan ATC
Journal nameClinical Cancer Research
Year2008
Month11
Day1
Volume Number14
Issue Number21
PublisherAMER ASSOC CANCER RESEARCH
Pages7080 - 7087
ISSN1078-0432
eISSN1557-3265
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesOncology; ONCOLOGY

Last updated on 2021-15-01 at 00:44