Highly effective antibacterial activity and synergistic effect of Ag-MgO nanocomposite against Escherichia coli
Publication in refereed journal


摘要Ag-MgO nanocomposite, synthesized by loading small-sized Ag nanoparticles on the surface of MgO nanoparticles, was firstly used as an effective antibacterial agent against Escherichia coli. The microstructure, morphology and composition of the nanocomposite were examined by X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM) equipped with an energy-dispersive X-ray (EDX) analyzer, X-ray photoelectron spectroscopy (XPS), BrunauereEmmetteTeller (BET) and flame atomic emission spectroscopy (FAES) measurements. An interfacial interaction between Ag and MgO was confirmed by XRD and XPS analyses, which could effectively inhibit the release of silver ions (Ag+) from the nanocomposite. Antibacterial tests showed that the as-prepared Ag-MgO nanocomposite exhibited stronger antibacterial activity against Escherichia coli, compared to pure MgO and equivalent Ag nanoparticles alone, indicating a synergistic effect between Ag and MgO. Based on the results of reactive oxygen species (ROS) detection, the enhanced antibacterial activity of Ag-MgO nanocomposite was attributed to the promotion of ROS production, because Ag particles on the surface of MgO are in favor of electron transfer, which could enhance ROS production via one-electron reduction of oxygen. Taking into consideration easy preparation, low cost, low release rate of Ag+, and high antibacterial activity of Ag-MgO nanocomposite, it is a very promising candidate material for bacterial disinfection. (C) 2016 Elsevier B.V. All rights reserved.
著者Zhu XW, Wu D, Wang W, Tan FT, Wong PK, Wang XY, Qiu XL, Qiao XL
期刊名稱Journal of Alloys and Compounds
頁次282 - 290
關鍵詞Ag nanoparticle; Antibacterial activity; Escherichia coli; MgO nanoparticle; Nanocomposite; Synergistic effect
Web of Science 學科類別Chemistry; Chemistry, Physical; Materials Science; Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering

上次更新時間 2020-28-09 於 02:07