A convenient method for the synthesis of alpha-carboxylate ester bromolactones via bromolactonization of alkenoic diesters
Publication in refereed journal

香港中文大學研究人員

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摘要We developed a simple and efficient method to construct a variety of alpha-ester bromolactones in good to excellent yields with high diastereoselectivies. The protocol uses readily prepared malonate ester derivatives as substrates, water as an additive and inexpensive N-bromosuccinimide as the halogen source; no catalyst or toxic additive is required. The resulting substituted bromolactones are the fundamental units of many useful molecules.
著者Wong YC, Yeung YY
期刊名稱Organic and Biomolecular Chemistry
出版年份2016
月份1
日期1
卷號14
期次12
出版社ROYAL SOC CHEMISTRY
頁次3202 - 3206
國際標準期刊號1477-0520
電子國際標準期刊號1477-0539
語言英式英語
Web of Science 學科類別Chemistry; Chemistry, Organic

上次更新時間 2021-04-12 於 00:33