Anti-human immunodeficiency virus (anti-HIV) natural products with special emphasis on HIV reverse transcriptase inhibitors
Publication in refereed journal


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摘要This review article aims at summarizing research findings concerning natural products which are endowed with the ability to inhibit human immunodeficiency virus (HIV). An emphasis is placed on HIV reverse transcriptase inhibitors because the bulk of the literature is focused on these compounds. It was found that a spectacular diversity of chemical structures encompassing proteins, terpenoids, coumarins, xanthones, alkaloids, flavonoids, polyphenols, and polysaccharides, which are elaborated by plant species as phylogenetically remote as the algae, gymnosperms and angiosperms, were capable of rendering the retroviral enzyme less active. The literature pertaining to natural products with HIV protease and integrase inhibitory activites is less voluminous.
著者Ng TB, Huang B, Fong WP, Yeung HW
期刊名稱Life Sciences
出版年份1997
月份8
日期1
卷號61
期次10
出版社PERGAMON-ELSEVIER SCIENCE LTD
頁次933 - 949
國際標準期刊號0024-3205
電子國際標準期刊號1879-0631
語言英式英語
關鍵詞anti-human immunodeficiency virus; reverse transcriptase inhibitor
Web of Science 學科類別Medicine, Research & Experimental; MEDICINE, RESEARCH & EXPERIMENTAL; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY; Research & Experimental Medicine

上次更新時間 2020-13-10 於 02:53