Chondromyxoid fibroma-like osteosarcoma: A distinct variant of low-grade osteosarcoma
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摘要Chondromyrxoid fibroma-like osteosarcoma is a recently described, extremely rare subtype of low-grade osteosarcoma. Two such cases were encountered among 102 cases of osteosarcoma seen in the Prince of Wales Hospital, Hong Kong, between 1984 and 1994, The first patient, a 39-year-old woman. presented with a mass in her right maxilla which was resected and mistaken as a myxoma. The tumour recurred locally four years later and she now has extensive local recurrent disease six years after initial presentation and is amenable to support treatment only, The second patient, a 28-year-old man, had a pelvic tumour which recurred in the form of a polypoid left atrial tumour and pulmonary nodules six gears after operation, The left atrial tumour recurred one year after operation. and led to sudden death of the patient seven years after initial presentation, Radiologically, the tumours in both cases appeared as expansile osteolytic lesions with erosion of adjacent bone and infiltration into soft tissue, Histologically, they consisted of lobules of spindle, stellate or polygonal tumour cells showing mitotic activity and with moderate nuclear pleomorphism and hyperchromatism, set in a highly myxoid stroma superficially mimicking chondromyxoid fibroma. The histological hallmark was the direct production of osteoid by tumour cells. Chondromyxoid fibroma-like osteosarcoma merits recognition as a distinct variant of low-grade osteosarcoma for which early appropriate surgery is indicated.
著者Chow LTC, Lin J, Yip KMH, Kumta SM, Ahuja AT, King WWK, Lee JCK
期刊名稱Histopathology
出版年份1996
月份11
日期1
卷號29
期次5
出版社BLACKWELL SCIENCE LTD
頁次429 - 436
國際標準期刊號0309-0167
電子國際標準期刊號1365-2559
語言英式英語
關鍵詞chondromyxoid fibroma; chondromyxoid fibroma-like osteosarcoma; low-grade osteosarcoma; osteosarcoma
Web of Science 學科類別Cell Biology; CELL BIOLOGY; Pathology; PATHOLOGY

上次更新時間 2020-19-11 於 01:35