A polysaccharide-peptide complex from cultured mycelia of the mushroom Tricholoma mongolicum with immunoenhancing and antitumor activities
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AbstractA polysaccharide-peptide complex with immunoenhancing and antitumor activities was obtained from the mycelial culture of Tricholoma mongolicum, an edible mushroom found in Northern China. The polysaccharide-peptide complex had a molecular mass of 15.5 kDa, as estimated by gel filtration, and a carbohydrate-protein ratio of about 8:1 and was not adsorbed on DEAE - Sepharose CL-6B. It possessed the activities of activating macrophages, stimulating macrophage antigen-presenting activity, which in turn enhanced proliferation of T-cells, and inhibiting the growth of sarcoma 180 cells that had been implanted in mice.
All Author(s) ListWang HX, Ng TB, Ooi VEC, Liu WK, Chang ST
Journal nameBiochemistry and Cell Biology
Volume Number74
Issue Number1
Pages95 - 100
LanguagesEnglish-United Kingdom
Keywordsantitumor activity; immunoenhancing activity; polysaccharide-peptide complex; Tricholoma mongolicum
Web of Science Subject CategoriesBiochemistry & Molecular Biology; BIOCHEMISTRY & MOLECULAR BIOLOGY; Cell Biology; CELL BIOLOGY

Last updated on 2021-02-05 at 02:09