IMMUNOMODULATORY AND ANTITUMOR POLYSACCHARIDES FROM MEDICINAL-PLANTS
Publication in refereed journal


Times Cited
Web of Science64WOS source URL (as at 01/07/2020) Click here for the latest count
Altmetrics Information
.

Other information
AbstractMany Chinese medicinal plants have immunomodulatory and anti-tumour activities. Most of the anti-tumour activities of these Chinese herbs are probably due to their immunostimulating polysaccharide components. A general scheme for the isolation and purification of the bioactive polysaccharides from naturally occurring medicinal plants is described. Hot-water extraction followed by various chromatographic methods are usually used to purify the bioactive polysaccharides. The different fractions separated from Chinese medicinal plants show a range of immunomodulatory and anti-tumour activities. The analytical methods used for monosaccharide sequence determination and structural elucidation of the bioactive polysaccharides are described, as are the tests used to evaluate their immunopharmacological activities, both in vitro and in vivo. The purification, characterization and structural elucidation of immunomodulatory polysaccharides from medicinal plants may have important implications in the immunotherapy of cancer and in the treatment of various other diseases.
All Author(s) ListWONG CK, LEUNG KN, FUNG KP, CHOY YM
Journal nameJournal of International Medical Research
Year1994
Month11
Day1
Volume Number22
Issue Number6
PublisherCAMBRIDGE MED PUBL
Pages299 - 312
ISSN0300-0605
LanguagesEnglish-United Kingdom
KeywordsANTITUMOR ACTIVITIES; IMMUNOSTIMULATING ACTIVITIES; MEDICINAL PLANTS; POLYSACCHARIDES
Web of Science Subject CategoriesMedicine, Research & Experimental; MEDICINE, RESEARCH & EXPERIMENTAL; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY; Research & Experimental Medicine

Last updated on 2020-02-07 at 05:37