CORRELATION OF SERUM OFLOXACIN CONCENTRATION AND SERUM CREATININE LEVEL IN PATIENTS ON PROLONGED THERAPY
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摘要Serum ofloxacin concentrations were assessed by high performance liquid chromatography 4h after drug administration in 86 patients with pulmonary tuberculosis. All patients had multidose, once-daily drug administration (200mg to 800mg p.o.) for at least 3 weeks prior to assessment. The serum creatinine levels were simultaneously assessed for these patients. A positive correlation was found between serum ofloxacin (Y) and serum creatinine x dose of ofloxacin administered/body surface area (X). The correlation can be represented mathematically by the equation: Y = 0.87X + 0.68 (r = 0.80, p < 0.001).
著者YEW WW, WONG CF, WONG PC, CHEUNG SW, CHAN CY, CHENG AFB
期刊名稱International Journal of Clinical Pharmacology Research
出版年份1993
月份1
日期1
卷號13
期次5
出版社BIOSCIENCE EDIPRINT INC
頁次243 - 245
國際標準期刊號0251-1649
語言英式英語
Web of Science 學科類別Pharmacology & Pharmacy
