A DOUBLE-BLIND RANDOMIZED COMPARISON OF PERINDOPRIL AND KETANSERIN IN THE TREATMENT OF HYPERTENSION IN ELDERLY DIABETIC-PATIENTS
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摘要A double-blind, randomised study of the antihypertensive efficacy of perindopril and ketanserin in 44 elderly noninsulin-dependent diabetic patients aged greater-than-or-equal-to 60 years was conducted. Blood pressure, blood biochemical and haematological parameters, plasma vasoactive hormones, urinary volume, electrolytes and microalbumin were measured at baseline, after a 4-week placebo period, and at intervals during 8 weeks of treatment with active drug. Electrocardiogram and echocardiogram data were also obtained. Dosages of perindopril used were 2mg once daily for 4 weeks doubling to 4mg once daily if a target blood pressure of less-than-or-equal-to 160/90mm Hg was not reached. Dosages of ketanserin were 40mg twice daily increasing to 80mg twice daily.
著者WOO J, WOO KS, OR KH, COCKRAM CS, NICHOLLS MG
期刊名稱Drugs and Aging
出版年份1993
月份11
日期1
卷號3
期次6
出版社ADIS INTERNATIONAL LTD
頁次525 - 531
國際標準期刊號1170-229X
電子國際標準期刊號1179-1969
語言英式英語
Web of Science 學科類別Geriatrics & Gerontology; GERIATRICS & GERONTOLOGY; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

上次更新時間 2021-17-01 於 00:42