MOLECULAR STUDIES OF PLASMIDS OF MULTIPLY-RESISTANT SHIGELLA SPP IN HONG-KONG
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摘要One hundred and two Shigella spp. isolated in two hospitals in Hong Kong were analysed for antibiotic resistances, resistance plasmids and plasmid profiles. Three quarters of the isolates were S. flexneri. All isolates harboured plasmids, up to a maximum of ten within one strain. Plasmids of 220 kb encoding resistances to tetracycline, chloramphenicol and sulphonamide and probably also associated with invasiveness in the Sereny test were found in 80 strains and were transferable in 18% of cases. Resistance plasmids of 92 and 99 kb were found in 27 and 15 strains respectively and encoded resistances to ampicillin, tetracycline, chloramphenicol, kanamycin, sulphonamide, trimethoprim, cotrimoxazole and gentamicin; these plasmids were usually transferable. Four plasmids of 3.9, 2.8, 2.2 and 1.8 kb were commonly found in S. flexneri strains, but were rare in other species. In contrast, there was no predominant plasmid profile in S. sonnei. S. flexneri is endemic in Hong Kong and these plasmid studies suggest that the strains in circulation are derived from only a few clones.
著者LING JM, SHAW PC, KAM KM, CHENG AF, FRENCH GL
期刊名稱Epidemiology and Infection
出版年份1993
月份6
日期1
卷號110
期次3
出版社CAMBRIDGE UNIV PRESS
頁次437 - 446
國際標準期刊號0950-2688
電子國際標準期刊號1469-4409
語言英式英語
Web of Science 學科類別Infectious Diseases; INFECTIOUS DISEASES; Public, Environmental & Occupational Health; PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH, SCI

上次更新時間 2021-17-02 於 23:58