LIPIDS, LIPOPROTEINS AND OTHER CORONARY RISK-FACTORS IN CHINESE MALE SURVIVORS OF MYOCARDIAL-INFARCTION
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摘要Objective: To assess the importance of an abnormal lipid profile as a risk factor in relation to nonbiochemical risk factors, and to define the risk levels for lipid, lipoprotein and apolipoprotein in a Chinese population. Patients and Methods: Serum lipids, lipoproteins, apolipoproteins and other cardiovascular risk factors were studied in 89 Chinese men 3 months after acute myocardial infarction and 56 controls. Results: Cases had higher mean total cholesterol (TC), LDL- and VLDL-cholesterol, triglycerides and apolipoprotein B (Apo B), and lower mean HDL-cholesterol and apolipoprotein AI (Apo AI). Mean BMI was also higher, as was the prevalence of smokers and subjects with a history of hypertension. In univariate analysis, the odds ratios for TG greater-than-or-equal-to 1.6 mmol/l, LDL-cholesterol greater-than-or-equal-to 4.1 mmol/l, VLDL-cholesterol greater-than-or-equal-to 0.73 mmol/l, Apo B greater-than-or-equal-to 104 mg/dl were of the same order of magnitude as being a current smoker, having a BMI greater-than-or-equal-to 24.3 kg/m2, and a history of hypertension. High HDL-cholesterol (greater-than-or-equal-to 1.39 mmol/l) and Apo Al (greater-than-or-equal-to 139 mg/dl) were protective factors. The odds ratios for successively higher quartile values of cholesterol were not statistically significant. Multiple logistic regression identified smoking habit, history of hypertension, obesity, high Apo B and low Apo Al concentrations as independent risk factors for myocardial infarction. Conclusions: In a Chinese population, low serum Apo Al and high Apo B are risk factors for myocardial infarction of a comparable magnitude to smoking, hypertension and obesity.
著者WOO J, HO SC, WONG SL, WOO KS, TSE CY, CHAN KK, KAY CS, MAK WP, CHEUNG KO, LAM CWK, DONNAN SPB
期刊名稱International Journal of Cardiology
出版年份1993
月份6
日期1
卷號39
期次3
出版社ELSEVIER SCI IRELAND LTD
頁次195 - 202
國際標準期刊號0167-5273
電子國際標準期刊號1874-1754
語言英式英語
關鍵詞APOLIPOPROTEIN; CHINESE; LIPIDS; LIPOPROTEIN; MYOCARDIAL INFARCTION; RISK FACTORS
Web of Science 學科類別Cardiac & Cardiovascular Systems; CARDIAC & CARDIOVASCULAR SYSTEMS; Cardiovascular System & Cardiology

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