POSTANTIBIOTIC EFFECTS OF AMIKACIN AND OFLOXACIN ON MYCOBACTERIUM-FORTUITUM
Publication in refereed journal

香港中文大學研究人員

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摘要A study of postantibiotic effects (PAE) in vitro of amikacin and ofloxacin on Mycobacterium fortuitum isolates from sternotomy wounds by use of the dilution method for drug removal showed that both drugs exhibited good bactericidal activities, with the PAE of amikacin lasting from 13.5 to 27.6 h and the PAE of ofloxacin lasting from 1.2 to 5.0 h. These laboratory results concur with our experience of the efficacy of once-daily dosing with these drugs in the treatment of infections caused by M. fortuitum. These data may have therapeutic implications in guiding the scheduling of the administration of drugs in these infections, which require a long duration of therapy.
著者TSUI SYT, YEW WW, LI MSK, CHAN CY, CHENG AFB
期刊名稱Antimicrobial Agents and Chemotherapy
出版年份1993
月份5
日期1
卷號37
期次5
出版社AMER SOC MICROBIOLOGY
頁次1001 - 1003
國際標準期刊號0066-4804
電子國際標準期刊號1098-6596
語言英式英語
Web of Science 學科類別Microbiology; MICROBIOLOGY; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

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