CGRP-IMMUNOREACTIVITY IN MERKEL CELLS AND NONMYELINATED NERVE PLEXUSES OF DOG SKIN
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香港中文大學研究人員

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摘要IN dog skin Merkel cells, calcitonin gene-related peptide (CGRP) immunoreactivity was consistently encountered at the subcellular dense-core granule region. The immunogold particles used as a marker for CGRP, were located specifically in and around the dense-core granules. They were also found in the surrounding cytoplasm close to the dense-core granules. Nerve terminals supplying the Merkel cell were CGRP-negative. CGRP-immunoreactive nonmyelinated nerve fibres were also found in the same specimen. These nonmyelinated nerve fibres were ensheathed by Schwann cell cytoplasm. The gold particles were only located in the dense-core granules of the axis cylinders. It is concluded that a CGRP-like substance predominantly accumulates in the dense-core granules of dog Merkel cells as well as in cutaneous nonmyelinated fibres.
著者CHEW SBC, LEUNG PY
期刊名稱NeuroReport
出版年份1993
月份4
日期1
卷號4
期次4
出版社RAPID SCIENCE PUBLISHERS
頁次457 - 459
國際標準期刊號0959-4965
電子國際標準期刊號1473-558X
語言英式英語
關鍵詞CGRP; CUTANEOUS NERVE; EM IMMUNOCYTOCHEMISTRY; MERKEL CELL
Web of Science 學科類別Neurosciences; NEUROSCIENCES; Neurosciences & Neurology

上次更新時間 2021-17-02 於 23:57