ANTITUMOR EFFECT OF CHEMICALLY SYNTHESIZED (+)-GONIOPYPYRONE
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AbstractChemically synthesized (+)-goniopypyrone was found to suppress the growth of cultured Ehrlich ascites tumor cells as well as PU5-1.8 cells. The ED50 values were found to be 35 and 30 mug/ml for the two cell lines used. An LD50 of 193 mug/ml was observed in the brine shrimp bioassay.
All Author(s) ListSHING TKM, LOOK M, CHOY YM
Journal nameChemotherapy
Year1993
Month3
Day1
Volume Number39
Issue Number2
PublisherKARGER
Pages132 - 134
ISSN0009-3157
LanguagesEnglish-United Kingdom
Keywords(+)-EPI-GONIOTRIOL; (+)-GONIOPYPYRONE; EHRLICH ASCITES TUMOR; PU5-18
Web of Science Subject CategoriesOncology; ONCOLOGY; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

Last updated on 2020-02-07 at 02:28