CYTODIAGNOSIS OF 112 SALIVARY-GLAND LESIONS - CORRELATION WITH HISTOLOGIC AND FROZEN SECTION DIAGNOSIS
Publication in refereed journal


Full Text

Times Cited
Web of Science66WOS source URL (as at 28/05/2020) Click here for the latest count

Other information
AbstractAspirates of 112 cases of salivary gland lesions with histologic correlation were reviewed. Fifty-five cases (49%) had frozen sections made. The 112 cases included 76 cases of benign lesions (31 cases of pleomorphic adenoma, 19 of Warthin's tumor and 26 of nonneoplastic lesions), 22 of primary salivary gland malignancy and 14 of metastatic malignant lesions. The overall accuracy in diagnosing benign and malignant lesions was 95%. The accuracy in diagnosing the exact category of neoplastic lesions was 70%. The diagnostic sensitivity for malignant lesions was 86% and the specificity, 99%. There was one false positive, in which a pleomorphic adenoma was diagnosed as small cell carcinoma. Five false-negative cases were encountered that were due to under-diagnosis of mucoepidermoid carcinoma and adenoid cystic carcinoma. The smears were reviewed, and the diagnostic pitfalls are discussed. A comparison of the cytodiagnosis and frozen section diagnosis was made. In frozen sections there were two false negatives, and two diagnoses were deferred. The overall diagnostic accuracy was 91%. The accuracy in diagnosing the exact category of neoplastic disease was 77%. The diagnostic sensitivity for malignant disease was 70% and specificity, 100%. Frozen section, however, did supplement the fine needle aspiration diagnosis in 13 cases.
All Author(s) ListCHAN MKM, MCGUIRE LJ, KING W, LI AKC, LEE JCK
Journal nameActa Cytologica
Year1992
Month5
Day1
Volume Number36
Issue Number3
PublisherSCI PRINTERS & PUBL INC
Pages353 - 363
ISSN0001-5547
eISSN1938-2650
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesCell Biology; CELL BIOLOGY; Pathology; PATHOLOGY

Last updated on 2020-29-05 at 00:49