FATAL ADULT HENOCH-SCHONLEIN PURPURA DUE TO SMALL INTESTINAL INFARCTION
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摘要A 57-year-old woman presented with classical symptoms of Henoch-Schonlein purpura including arthralgia, abdominal pain, palpable purpuric rash and abnormalities of the urinary sediments. The clinical course was subsequently complicated by severe paralytic ileus leading to respiratory embarrassment. Laparotomy confirmed patchy areas of small bowel infarction due to necrotizing vasculitis. Skin biopsy revealed extensive leukocytoclastic vasculitis with granular deposits of IgA in the blood vessels. Anti-neutrophil cytoplasmic autoantibodies (ANCA) were not detectable. The patient continued to deteriorate despite bowel resection, intensive immunosuppressive therapy and plasma exchange, and eventually died. Gastrointestinal involvement in adult Henoch-Schonlein purpura has previously been reported to have a favourable clinical course. However, our case illustrates the rare but lethal complication of intestinal infarction in patients who fail to respond to conservative treatment.
著者CHAN JCN, LI PKT, LAI FM, LAI KN
期刊名稱Journal of Internal Medicine
出版年份1992
月份8
日期1
卷號232
期次2
出版社BLACKWELL SCIENCE LTD
頁次181 - 184
國際標準期刊號0954-6820
語言英式英語
關鍵詞HENOCH-SCHONLEIN PURPURA; SMALL INTESTINAL INFARCTION
Web of Science 學科類別General & Internal Medicine; Medicine, General & Internal; MEDICINE, GENERAL & INTERNAL

上次更新時間 2021-25-02 於 02:07