DIAGNOSIS OF TUBERCULOUS MENINGITIS BY DETECTION OF TUBERCULOSTEARIC ACID IN CEREBROSPINAL-FLUID
Publication in refereed journal


Full Text

Times Cited
Web of Science8WOS source URL (as at 27/01/2021) Click here for the latest count

Other information
AbstractTuberculous meningitis still poses a major diagnostic problem. Recently, several new techniques for rapid diagnosis of tuberculous meningitis have been developed. One of these newer techniques is the detection of mycobacterial fatty acids, using gas chromatography-mass spectroscopy. In this study we evaluated the sensitivity and specificity of this recently reported method in a blind trial. The sensitivity was found to be 100%, specificity only 91%. The number of false positive results limits the value of this test in the primary diagnosis of tuberculous meningitis. Nonetheless, we consider this method to be a valuable tool for establishing the diagnosis in culture-negative patients presenting with signs and symptoms suggestive of tuberculous meningitis,
All Author(s) ListLUEF G, ALLERBERGER F, CHENG A, CHAN C, BEREK K, PFAUSLER B, DIERICH M, SCHMUTZHARD E
Journal nameWiener Klinische Wochenschrift
Year1992
Month1
Day1
Volume Number104
Issue Number11
PublisherSPRINGER-VERLAG WIEN
Pages322 - 324
ISSN0043-5325
LanguagesEnglish-United Kingdom
KeywordsSENSITIVITY; SPECIFICITY; TUBERCULOSTEARIC ACID; TUBERCULOUS MENINGITIS
Web of Science Subject CategoriesGeneral & Internal Medicine; Medicine, General & Internal; MEDICINE, GENERAL & INTERNAL

Last updated on 2021-28-01 at 00:25