ASCENDING INFECTION OF THE BILIARY-TRACT AFTER SURGICAL SPHINCTEROTOMY AND BILIARY STENTING
Publication in refereed journal

香港中文大學研究人員

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摘要It has been widely accepted that there is an ascending route of bacterial infection of the biliary tract but there is a lack of direct evidence. This hypothesis was tested in an animal experiment using the cat as an animal model. The implantation of biliary stents and surgical sphincterotomy were performed in these animals, with sham controls. Stents bypassing the sphincter of Oddi with the tip in the duodenal lumen were colonized by duodenal micro-organisms and the biliary tract was heavily contaminated. Blockage of these stents resulted in biliary obstruction. Stents implanted within the common bile duct, proximal to the sphincter were largely unaffected by biofilm formation. After surgical sphincterotomy the biliary tract was also contaminated but, in the absence of obstruction, the animals did not develop any symptoms. It was concluded that ascending infection by duodenal biliary reflux, via the sphincter of Oddi, is an important route of infection in the biliary system.
著者SUNG JY, LEUNG JWC, SHAFFER EA, LAM K, OLSON ME, COSTERTON JW
期刊名稱Journal of Gastroenterology and Hepatology
出版年份1992
月份5
日期1
卷號7
期次3
出版社BLACKWELL SCIENCE
頁次240 - 245
國際標準期刊號0815-9319
電子國際標準期刊號1440-1746
語言英式英語
關鍵詞BACTERIA; BILIARY STENT; BIOFILM; SPHINCTEROTOMY
Web of Science 學科類別Gastroenterology & Hepatology; GASTROENTEROLOGY & HEPATOLOGY

上次更新時間 2020-22-11 於 01:45