D-MANNOSE AS A PRESERVATIVE OF GLUCOSE IN BLOOD-SAMPLES
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AbstractWe studied the changes in blood glucose concentration in blood samples collected in heparinized specimen tubes containing no other preservative, or containing NaF, D-mannose, or a combination of NaF and D-mannose. Blood concentration in samples taken into NaF decreased by 0.40 mmol/L in the first 2 h; thereafter, there was no change. In samples collected into mannose there was a small but significant decrease in blood glucose concentration with time. When samples containing mannose were analyzed immediately after collection, the concentration of glucose was higher than in later analyses, probably because of an exchange of intracellular glucose for extracellular mannose. When a combination of NaF and mannose was used, the blood glucose concentration was relatively stable but slightly higher than nonpreserved samples for the next 24 h. However, samples containing mannose were unsuitable for electrolyte analysis. We conclude that a combination of D-mannose and NaF may be a better preservative for blood glucose than either compound alone.
All Author(s) ListCHAN AYW, HO CS, CHAN TYK, SWAMINATHAN R
Journal nameClinical Chemistry
Year1992
Month3
Day1
Volume Number38
Issue Number3
PublisherAMER ASSOC CLINICAL CHEMISTRY
Pages411 - 413
ISSN0009-9147
eISSN1530-8561
LanguagesEnglish-United Kingdom
KeywordsELECTROLYTES; ENZYMATIC METHODS; SAMPLE HANDLING
Web of Science Subject CategoriesMedical Laboratory Technology; MEDICAL LABORATORY TECHNOLOGY

Last updated on 2020-22-10 at 00:31