IMMUNOCYTOCHEMICAL EVIDENCE OF A MET-ENKEPHALIN-LIKE SUBSTANCE IN THE DENSE-CORE GRANULES OF MOUSE MERKEL CELLS
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香港中文大學研究人員
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摘要The electron-microscopic immunogold method was applied to Merkel cells of adult mice to demonstrate the subcellular localization of met-enkephalin-like immunoreactivity. Post-embedding incubation with met-enkephalin antisera showed that the gold particles were associated with the dense-core granules of the Merkel cells. The majority, but not all, of the dense-core granules were strongly labelled. Osmication caused a significant reduction in the number of gold particles on these granules. The nerve terminal associated with the Merkel cell did not show met-enkephalin-like immunoreactivity. To the best of our knowledge, this is the first report of the ultrastructural localization of a positive met-enkephalin immunoreactivity in the dense-core granules of Merkel cells in mice.
著者CHEW SBC, LEUNG PY
期刊名稱Cell and Tissue Research
出版年份1991
月份9
日期1
卷號265
期次3
出版社SPRINGER VERLAG
頁次611 - 614
國際標準期刊號0302-766X
語言英式英語
關鍵詞DENSE-CORE GRANULES; IMMUNOCYTOCHEMISTRY; MERKEL CELLS; MET-ENKEPHALIN; MOUSE (ICR)
Web of Science 學科類別Cell Biology; CELL BIOLOGY

上次更新時間 2021-13-05 於 02:24