Plasminogen activator inhibitor-1 polymorphism is associated with progressive renal dysfunction after acute rejection in renal transplant recipients
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AbstractBackground. Plasma level of plasminogen activator inhibitor (PAI)-1 is genetically determined by a polymorphism in the promoter region, involving two alleles, 4G and 5G. Plasma PAI-1 concentrations are higher in subjects homozygous for the 4G allele than other genotypes (5G/5G and 4G/5G). Such genetic variation in fibrinolytic system may affect the long-term renal transplant outcome.
All Author(s) ListChow KM, Szeto CC, Szeto CYK, Poon P, Lai FMM, Li PKT
Journal nameTransplantation
Detailed description2002.
Year2002
Month12
Day27
Volume Number74
Issue Number12
PublisherLIPPINCOTT WILLIAMS & WILKINS
Pages1791 - 1794
ISSN0041-1337
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesImmunology; IMMUNOLOGY; Surgery; SURGERY; Transplantation; TRANSPLANTATION

Last updated on 2020-22-11 at 01:05