Plasminogen activator inhibitor-1 polymorphism is associated with progressive renal dysfunction after acute rejection in renal transplant recipients
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AbstractBackground. Plasma level of plasminogen activator inhibitor (PAI)-1 is genetically determined by a polymorphism in the promoter region, involving two alleles, 4G and 5G. Plasma PAI-1 concentrations are higher in subjects homozygous for the 4G allele than other genotypes (5G/5G and 4G/5G). Such genetic variation in fibrinolytic system may affect the long-term renal transplant outcome.
All Author(s) ListChow KM, Szeto CC, Szeto CYK, Poon P, Lai FMM, Li PKT
Journal nameTransplantation
Detailed description2002.
Volume Number74
Issue Number12
Pages1791 - 1794
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesImmunology; IMMUNOLOGY; Surgery; SURGERY; Transplantation; TRANSPLANTATION

Last updated on 2020-22-11 at 01:05