Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis
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AbstractBackground: Current guidelines recommend that patients at risk for ulcer disease who require treatment for arthritis receive nonsteroidal antiinflammatory drugs (NSAIDs) that are selective for cyclooxygenase-2 or the combination of a nonselective NSAID with a proton-pump inhibitor. We assessed whether celecoxib would be similar to diclofenac plus omeprazole in reducing the risk of recurrent ulcer bleeding in patients at high risk for bleeding.
All Author(s) ListChan FKL, Hung LCT, Suen BY, Wu JCY, Lee KC, Leung VKS, Hui AJ, To KF, Leung WK, Wong VWS, Chung SCS, Sung JJY
Journal nameNew England Journal of Medicine
Year2002
Month12
Day26
Volume Number347
Issue Number26
PublisherMASSACHUSETTS MEDICAL SOC/NEJM
Pages2104 - 2110
ISSN0028-4793
eISSN1533-4406
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesGeneral & Internal Medicine; Medicine, General & Internal; MEDICINE, GENERAL & INTERNAL

Last updated on 2020-22-11 at 01:05