Mechanism of lonidamine inhibition of the CFTR chloride channel
Publication in refereed journal

香港中文大學研究人員

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其它資訊
摘要1 The cystic fibrosis transmembrane conductance regulator (CFTR) Cl-channel is blocked by a broad range of organic anionic compounds. Here we investigate the effects of the indazole compound lonidamine on CFTR channels expressed in mammalian cell lines using patch clamp recording.
著者Gong XD, Burbridge SM, Lewis AC, Wong PYD, Linsdell P
期刊名稱British Journal of Pharmacology
出版年份2002
月份11
日期1
卷號137
期次6
出版社NATURE PUBLISHING GROUP
頁次928 - 936
國際標準期刊號0007-1188
電子國際標準期刊號1476-5381
語言英式英語
關鍵詞binding site; CFTR; chloride channel; indazole; open channel block; spectral analysis
Web of Science 學科類別Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

上次更新時間 2021-01-03 於 01:15