Randomized controlled study of colloid preload before spinal anaesthesia for Caesarean section
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摘要We randomized women having elective Caesarean section to receive either no preload (control group, n=33) or 4% gelatin solution (Gelofusine) 15 ml kg(-1) (colloid group, n=35) i.v. before spinal anaesthesia. Intravenous metaraminol was titrated at 0.25-0.75 mg min(-1) to maintain systolic arterial pressure (SAP) in the target range 90-100% of baseline after the spinal injection. The control group required more vasopressor in the first 10 min [median 1.7 (range 0-2.9) mg vs 1.4 (0-2.8), P=0.02] at a greater maximum infusion rate [0.5 (0-0.75) vs 0.25 (0-0.5) mg min(-1), P=0.0005] and had a lower minimum SAP [90 (51-109) vs 101 (75-127) mm Hg, P=0.006] than the colloid group. Nausea was less frequent in the colloid group (6 vs 24%) but neonatal outcome was similar in the two groups. Colloid preload improved haemodynamic stability but did not affect neonatal outcome when arterial pressure was maintained with an infusion of metaraminol during spinal anaesthesia for Caesarean section.
著者Kee WDN, Khaw KS, Lee BB, Ng FF, Wong MMS
期刊名稱British Journal of Anaesthesia
出版年份2001
月份11
日期1
卷號87
期次5
出版社OXFORD UNIV PRESS
頁次772 - 774
國際標準期刊號0007-0912
電子國際標準期刊號1471-6771
語言英式英語
關鍵詞anaesthesia, obstetric; anaesthetic techniques, subarachnoid; colloids, gelatin; complications, hypotension
Web of Science 學科類別Anesthesiology; ANESTHESIOLOGY

上次更新時間 2021-16-01 於 00:51