Altered expression of extracellular matrix and proteinases in noble rat prostate gland after long-term treatment with sex steroids
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AbstractBackground. Interactions between the epithelial cells and stromal tissues, which include the epithelial basement membrane, extracellular matrix, inducible factors, and various cell types, are believed to play a significant role in prostate gland carcinogenesis. Remodeling of extracellular matrix and degradation of basement membrane are the prerequisites for tumor cell invasion, and these changes are correlated with the expression of various proteinases.
All Author(s) ListLi SC, Chen GF, Chan PSF, Choi HL, Ho SM, Chan FL
Journal nameProstate
Volume Number49
Issue Number1
Pages58 - 71
LanguagesEnglish-United Kingdom
Keywordsbasement membrane; epithelial-stromal interactions; extracellular matrix; Noble rat prostate; prostate carcinogenesis; proteinases
Web of Science Subject CategoriesEndocrinology & Metabolism; ENDOCRINOLOGY & METABOLISM; Urology & Nephrology; UROLOGY & NEPHROLOGY

Last updated on 2021-22-09 at 23:54