Metaraminol infusion for maintenance of arterial blood pressure during spinal anesthesia for cesarean delivery: The effect of a crystalloid bolus
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摘要We randomly allocated women having elective cesarean delivery to receive either no bolus (Control Group, n = 31) or 20 mL/kg lactated Ringer's solution (Bolus Group, n = 35) IV before spinal anesthesia. An infusion of metaraminol started at 0.25 mg/min was titrated to maintain systolic arterial blood pressure in the target range 90%-100% of baseline. The total dose of metaraminol required up to the time of uterine incision was similar between the Control Group and the Bolus Group (3.62 +/- 1.20 vs 3.27 +/- 1.39 mg, P = 0.3). However, the Control Group required more metaraminol in the first 5 min (1.29 +/- 0.60 vs 0.96 +/- 0.58 mg, P = 0.025) and a faster maximum infusion rate (0.45 +/- 0.20 vs 0.32 +/- 0.13 mg/min, P = 0.002) compared with the Bolus Group. There was no difference between groups in regards to changes in systolic arterial blood pressure or heart rate over time, or maternal or neonatal outcome. We conclude that when metaraminol is used to maintain arterial pressure during spinal anesthesia for cesarean delivery, crystalloid bolus is not essential provided that sufficient vasopressor is given in the immediate postspinal period.
著者Kee WDN, Khaw KS, Lee BB, Wong MMS, Ng FF
期刊名稱Anesthesia and Analgesia
出版年份2001
月份9
日期1
卷號93
期次3
出版社LIPPINCOTT WILLIAMS & WILKINS
頁次703 - 708
國際標準期刊號0003-2999
電子國際標準期刊號1526-7598
語言英式英語
Web of Science 學科類別Anesthesiology; ANESTHESIOLOGY

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