A prospective study of the effect of botulinum toxin A on masseteric muscle hypertrophy with ultrasonographic and electromyographic measurement
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摘要We evaluated the effect of botulinum toxin A on masseteric muscle hypertrophy by using ultrasound and electromyography. Five patients (four with bilateral and one with unilateral masseteric muscle hypertrophy) were studied prospectively. In each patient, ultrasound-guided percutaneous intramuscular injection of botulinum toxin A was carried out. The change in muscle bulk was evaluated using serial ultrasonography and the electrical activity was assessed with electromyography. All five patients (nine hypertrophic muscles) showed a good response, with the maximal effect of a 31% reduction in muscle bulk seen 3 months after treatment. The effect remained stable one year after injection for six of the hypertrophic muscles, whereas three muscles needed a second injection to maintain the atrophy. This preliminary prospective study suggests that botulinum toxin A is a safe alternative method of treating masseteric muscle hypertrophy. However, the effect may be temporary and further intramuscular injection may be required to maintain atrophy. (C) 2001 The British Association of Plastic Surgeons.
著者To EWH, Ahuja AT, Ho WS, King WWK, Wong WK, Pang PCW, Hui ACF
期刊名稱British Journal of Plastic Surgery
出版年份2001
月份4
日期1
卷號54
期次3
出版社CHURCHILL LIVINGSTONE
頁次197 - 200
國際標準期刊號0007-1226
語言英式英語
關鍵詞botulinum toxin A; electromyographic monitoring; masseteric muscle hypertrophy; ultrasound monitoring
Web of Science 學科類別Surgery

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