In silico studies of energy metabolism of normal and diseased heart
Publication in refereed journal


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其它資訊
摘要Biotechnology research is developing into genomic analyses that involve the simultaneous monitoring of thousands of genes. The development of various bioinformatics resources that provide efficient access to information is necessary. We have used single-pass sequencing of randomly selected cDNA clones to generate expressed sequence tags (ESTs). These ESTs data has been widely used to study gene expression in a variety of heart libraries [1, 2]. Data annotation on our recent finding allows us to construct the profiles of genes in the energy metabolizing pathways (glycolysis and glycogen metabolism) that are expressed in heart cDNA libraries. In silico studies of genes of energy metabolism yields data that are consistent with results derived from conventional metabolic experiments. The change in gene profiles describing the metabolism of diseased hearts is also presented here.
著者Ngai SM, Way MMY, Chan H, Tsui SKW, Lee CY, Fung KP
期刊名稱Molecular Biology Reports
出版年份2000
月份6
日期1
卷號27
期次2
出版社KLUWER ACADEMIC PUBL
頁次123 - 128
國際標準期刊號0301-4851
電子國際標準期刊號1573-4978
語言英式英語
關鍵詞energy metabolism; ESTs; heart; in silico
Web of Science 學科類別Biochemistry & Molecular Biology; BIOCHEMISTRY & MOLECULAR BIOLOGY

上次更新時間 2020-11-08 於 04:38