Central nervous system candidiasis in preterm infants: Limited value of biochemical markers for diagnosis
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摘要Two rare cases of isolated central nervous system (CNS) candidiasis in preterm infants have been diagnosed in a tertiary neonatal centre over the past 6 years. Despite the life-threatening nature of the disease, biochemical infection markers were not useful for the early identification of localized fungal infection. Because the infection was likely to have been blood borne, we postulated that the initial fungal load was probably low and that the organisms were rapidly eliminated from the circulation after a few had been deposited in the CNS. Hence, the absence of fungaemia or systemic involvement precluded the activation of cytokines and cellular markers. Clinicians should be aware of the limitation of biochemical infection markers so that diagnosis and treatment of fungal infection will not be delayed.
著者Ng PC, Lee CH, Fok TF, Chui K, Wong W, Cheung KL, So KW
期刊名稱Journal of Paediatrics and Child Health
出版年份2000
月份10
日期1
卷號36
期次5
出版社BLACKWELL SCIENCE ASIA
頁次509 - 510
國際標準期刊號1034-4810
電子國際標準期刊號1440-1754
語言英式英語
關鍵詞candida; infection markers; preterm
Web of Science 學科類別Pediatrics; PEDIATRICS

上次更新時間 2020-20-09 於 03:18