Acute renal failure in a patient with Rosai-Dorfman disease
Publication in refereed journal


引用次數
替代計量分析
.

其它資訊
摘要Acute renal failure developed in a 57-year-old woman who had Rosai-Dorfman disease diagnosed 1 year previously on a cervical lymph node. Organ imaging showed diffuse masses infiltrating both kidneys. The renal biopsy showed a lymphoplasmacytic and histiocytic process extensively replacing the parenchyma, which is in keeping with Rosai-Dorfman disease of the kidneys. However, the typical lymphophagocytic cells were lacking. This case illustrates that diagnosis of Rosai-Dorfman disease in renal biopsy can be very difficult, requiring both exclusion of many benign and malignant lesions and a high index of suspicion for this condition. In particular, lymphoma was excluded based on the mixed polyclonal composition of inflammatory cells and the absence of atypical lymphoid proliferation. The renal function partially recovered after a course of therapy combining VP-16 (etoposide) and dexamethasone and remained stable over 4-year follow-up. This report emphasizes the importance of early diagnosis and intervention to safeguard renal function in extensive Rosai-Dorfman disease. (C) 1999 by the National Kidney Foundation, Inc.
著者Lai FMM, To KF, Szeto CC, Wang AYM, Ahuja AT, Choi PCL, Leung CB, Kew J, Li PKT
期刊名稱American Journal of Kidney Diseases
出版年份1999
月份9
日期1
卷號34
期次3
出版社W B SAUNDERS CO
頁次art. no. - e12
國際標準期刊號0272-6386
電子國際標準期刊號1523-6838
語言英式英語
關鍵詞acute renal failure; emperipolesis; lymphadenopathy; pseudolymphoma; renal biopsy; Rosai-Dorfman disease
Web of Science 學科類別Urology & Nephrology; UROLOGY & NEPHROLOGY

上次更新時間 2021-16-09 於 01:20