Nasal manifestation of extranodal Rosai-Dorfman disease - diagnosis and management
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AbstractTwo cases of Rosai-Dorfman disease with polypoid nasal infiltration mimicking nasal tuberculosis and malignant lymphoma are reported. This rare benign disease was first described by Rosai and Dorfman in 1969 and is characterized by histiocytic proliferation. It is seldom considered in the differential diagnosis of granulomatous diseases due to its rarity and histological similarity to other diseases. Extranodal manifestations of this disease are uncommon. Although no specific treatment can guarantee a sustained remission of this disease, surgery for loco-regional lesions can result in long-term symptomatic control and restoration of function. Both patients underwent endoscopic resection of the nasal polypoid lesions and have subsequently been free of recurrence. Loco-regional infiltration of the nasal cavity by Rosai-Dorfman disease is effectively managed by endoscopic resection.
All Author(s) ListKu PKM, Tong MCF, Leung CY, Pak MW, van Hasselt CA
Journal nameJournal of Laryngology and Otology
Volume Number113
Issue Number3
Pages275 - 280
LanguagesEnglish-United Kingdom
Keywordshistiocytosis, sinus; nasal polyps; surgery, endoscopic
Web of Science Subject CategoriesOtorhinolaryngology; OTORHINOLARYNGOLOGY

Last updated on 2021-04-04 at 01:14